David L. Fabacher

Apparent Resistance To Pyrethroids In Organochlorine-Resistant Mosquitofish

Organochlorine-resistant mosquitofish from an insecticide contaminated environment in the Mississippi Delta showed a 3.4-fold tolerance to pyrethrum when compared to a susceptible strain. The 24-hr LC50 values for pyrethrum in susceptible and resistant mosquitofish were 27 and 93 ppb, respectively. Results of studies with sesamex, an inhibitor of mixed-function oxidase (mf0) enzymes, indicated that the tolerance to pyrethrum is partially, but not solely the result of increased levels of mfo enzymes. Additional studies with allethrin show that increased carboxylesterase enzyme levels cannot...