We present a framework for using Landtype Associations (LTAs), or subdivisions of ecological subsections, to develop integrated conservation strategies for priority bird and other taxa of conservation concern in the Central Hardwoods Bird Conservation Region, using the Missouri Ozarks as a prototype. We profile LTAs amenable to the conservation of species in grassland, shrub-savanna, woodland-forest and wetland landscapes, provide examples of priority species associated with each, suggest conservation strategies at biologically appropriate spatial scales, and evaluate conservation opportunities and limits based upon current land use characteristics and socioeconomic factors. Key words: Landtype associations, ecological hierarchy, bird conservation, comprehensive wildlife conservation strategies